Pilot Knob, MO is a city located in Iron County, Missouri and has a land area of 0.79 square miles (2.05 km2). The water area for the city is 0.00 square miles or 0.00 km2. There is one unique zip code in Pilot Knob, Missouri and it is 63663. The area code(s) for Pilot Knob is 573.
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